Haemorrhagic disease of the newborn

Haemorrhagic disease of the newborn.

There is a wide difference of opinion regarding the criteria necessary for the diagnosis of haemorrhagic disease of the newborn. Formerly, the essential feature seems to have been bleeding from the alimentary tract, hence the synonym 'melaena neonatorum.' More recently a wider view has been taken and many authorities do not consider that haemorrhage into the alimentary tract is necessary for di...

Secondary haemorrhagic disease of the newborn.

were born prematurely; 3 suffered birth asphyxia; and 3 became hypothermic. Laboratory studies showed fibrin degradation products, low platelet counts, and deficient coagulation factors. At necropsy extensive subarachnoid haemorrhages of a characteristic type were seen in all cases, and intravascular fibrin deposits in all but one. Haemorrhage in these babies is considered to be due to consumpt...

Late haemorrhagic disease of the newborn.

BACKGROUND Late haemorrhagic disease of the newborn (HDN) can occur owing to a lack of vitamin K prophylaxis, as a manifestation of an underlying disorder or idiopatically from the 8th day to 12 weeks after birth. METHODS Eight infants admitted to Kocaeli University Hospital with nine episodes of late HDN between January 2002 and April 2005 were evaluated retrospectively from hospital records...

Vitamin K and haemorrhagic disease of the newborn.

Haemorrhagic diseases of the newborn.

In 1997, the Canadian Paediatric Society revised its recommendations on the administration of vitamin K to newborn babies to prevent hemorrhagic disease of the newborn (HDNB). Although the previous guideline indicated that oral vitamin K prophylaxis was equivalent to intramuscular (IM), epidemiologic evidence suggested an increased relative risk of HDNB by a factor of 6.15 (the current guidelin...